Furans

Aromatic organic compounds that consist of a five-membered ring with four carbon atoms, one oxygen atom, and two double bonds.

1 – 15 of 20 results

Nifuroxazide, MedChemExpress

MedChemExpress Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	275.22
Color	Yellow
Physical Form	Solid
Chemical Name or Material	Nifuroxazide
Grade	Research
SMILES	O=C(N/N=C/C1=CC=C([N+]([O-])=O)O1)C2=CC=C(O)C=C2
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.51%
CAS	965-52-6
Solubility Information	DMSO : ≥ 155 mg/mL (563.19 mM)
Health Hazard 1	H302∣H312∣H332
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₂H₉N₃O₅
Formula Weight	275.22

MedChemExpress TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM and induces intrinsic apoptosis in several human cancer cell lines. TM5441 attenuates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	428.82
Color	Off-White
Physical Form	Solid
Chemical Name or Material	TM5441
Grade	Research
SMILES	ClC1=CC=C(NC(COCC(NC2=CC=CC(C3=COC=C3)=C2)=O)=O)C(C(O)=O)=C1
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.18%
CAS	1190221-43-2
Solubility Information	DMSO : ≥ 300 mg/mL (699.59 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₁H₁₇ClN₂O₆
Formula Weight	428.82

4E2RCat, MedChemExpress

MedChemExpress 4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 μM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	455.93
Color	Yellow
Physical Form	Solid
Chemical Name or Material	4E2RCat
Grade	Research
SMILES	O=C(O)C1=CC(C2=CC=C(/C=C(SC(N3CC4=CC=CC=C4)=S)/C3=O)O2)=CC=C1Cl
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	98.0%
CAS	432499-63-3
Solubility Information	DMSO : 23.33 mg/mL (51.17 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₂H₁₄ClNO₄S₂
Formula Weight	455.93

CX-6258, MedChemExpress

MedChemExpress CX-6258 is a potent and kinase selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	461.94
Color	Orange
Physical Form	Solid
Chemical Name or Material	CX-6258
Grade	Research
SMILES	O=C1NC2=CC=C(Cl)C=C2/C1=C\C3=CC=C(C4=CC=CC(C(N5CCCN(C)CC5)=O)=C4)O3
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.73%
CAS	1202916-90-2
Solubility Information	DMSO : ≥ 50 mg/mL (108.24 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₆H₂₄ClN₃O₃
Formula Weight	461.94

ML167, MedChemExpress

MedChemExpress ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, >10-fold selectivity for closely related kinases Clk1, Clk2, Clk3 and Dyrk1A/1B.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	335.36
Color	Khaki
Physical Form	Solid
Chemical Name or Material	ML167
Grade	Research
SMILES	OCC1=CC=C(C2=CC3=C(NCC4=CC=C(C)O4)N=CN=C3C=C2)O1
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.08%
CAS	1285702-20-6
Solubility Information	DMSO : 16.67 mg/mL (49.71 mM; Need ultrasonic)
Health Hazard 1	H302
Synonym	CID44968231 NCGC00188654
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₉H₁₇N₃O₃
Formula Weight	335.36

AGK2, MedChemExpress

MedChemExpress AGK2 is a selective SIRT2 inhibitor with an IC50 of 3.5 μM. AGK2 inhibits SIRT1 and SIRT3 with IC50s of 30 and 91 μM, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	434.27
Color	Green Yellow
Physical Form	Solid
Chemical Name or Material	AGK2
Grade	Research
SMILES	O=C(NC1=C2C=CC=NC2=CC=C1)/C(C#N)=C/C3=CC=C(C4=CC(Cl)=CC=C4Cl)O3
For Use With (Application)	Cancer-programmed cell death
Percent Purity	97.0%
CAS	304896-28-4
Solubility Information	DMSO : 12.5 mg/mL (28.78 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₁₃Cl₂N₃O₂
Formula Weight	434.27

C646, MedChemExpress

MedChemExpress C646 is a selective and competitive histone acetyltransferase p300 inhibitor with Ki of 400 nM, and is less potent for other acetyltransferases.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	445.42
Color	Red Brown
Physical Form	Solid
Chemical Name or Material	C646
Grade	Research
SMILES	O=C(O)C1=CC=C(N2N=C(C)/C(C2=O)=C\C3=CC=C(C4=CC(C)=C(C)C=C4[N+]([O-])=O)O3)C=C1
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.0%
CAS	328968-36-1
Solubility Information	DMSO : 16.67 mg/mL (37.43 mM; Need ultrasonic)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₄H₁₉N₃O₆
Formula Weight	445.42

4E1RCat, MedChemExpress

MedChemExpress 4E1RCat is an inhibitor of cap-dependent translation, and inhibits eIF4E:eIF4GI interaction, with an IC50 an of ∼4 μM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	478.45
Color	Dark Brown
Physical Form	Solid
Chemical Name or Material	4E1RCat
Grade	Research
SMILES	O=C(O)C1=CC=C(N2C(/C(C=C2C3=CC=CC=C3)=C\C4=CC=C(C5=CC=C([N+]([O-])=O)C=C5)O4)=O)C=C1
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.0%
CAS	328998-25-0
Solubility Information	DMSO : 18.33 mg/mL (38.31 mM; Need ultrasonic)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₈H₁₈N₂O₆
Formula Weight	478.45

Leukadherin-1, MedChemExpress

MedChemExpress Leukadherin-1, a specific agonist of the leukocyte surface integrin CD11b/CD18, increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC50 of 4 μM. Leukadherin-1 enhances leukocyte adhesion to ligands (such as ICAM-1) and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	421.49
Color	Orange
Physical Form	Solid
Chemical Name or Material	Leukadherin-1
Grade	Research
SMILES	O=C(O)C1=CC=C(C2=CC=C(/C=C(SC(N3CC4=CC=CC=C4)=S)/C3=O)O2)C=C1
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.0%
CAS	344897-95-6
Solubility Information	DMSO : 5 mg/mL (11.86 mM; Need ultrasonic)
Health Hazard 1	H302∣H410
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₂H₁₅NO₄S₂
Formula Weight	421.49

NSC59984, MedChemExpress

MedChemExpress NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway. NSC59984 acts by targeting GOF-mutant p53 and stimulates p73 to restore the p53 pathway signaling.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	265.27
Color	Yellow
Physical Form	Solid
Chemical Name or Material	NSC59984
Grade	Research
SMILES	O=C(N1CCN(C)CC1)/C=C/C2=CC=C([N+]([O-])=O)O2
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.76%
CAS	803647-40-7
Solubility Information	DMSO : 33.33 mg/mL (125.65 mM; Need ultrasonic)
Health Hazard 1	H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₂H₁₅N₃O₄
Formula Weight	265.27

PYR-41, MedChemExpress

MedChemExpress PYR-41 is a selective and cell permeable inhibitor of ubiquitin-activating enzyme E1 with an IC50 of < 10 μM, with little activity at E2 and E3.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	371.3
Color	Red browm
Physical Form	Solid
Chemical Name or Material	PYR-41
Grade	Research
SMILES	O=C(N1)/C(C(N1C2=CC=C(C=C2)C(OCC)=O)=O)=C/C3=CC=C([N+]([O-])=O)O3
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.0%
CAS	418805-02-4
Solubility Information	DMSO : ≥ 46 mg/mL (123.89 mM)
Health Hazard 1	H302∣H317
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₇H₁₃N₃O₇
Formula Weight	371.3

CID 2011756, MedChemExpress

MedChemExpress CID 2011756 is an ATP competitive PKD inhibitor, with an IC50 of 3.2 μM for PKD1 in cell free assay, and also shows cellular pan-PKD inhibitory activity against PKD2 and PKD3 (IC50, 0.6 and 0.7 μM, respectively). CID 2011756 also has antitumor activity.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	396.87
Color	Off-White
Physical Form	Solid
Chemical Name or Material	CID 2011756
Grade	Research
SMILES	O=C(C1=CC=C(C2=CC=CC(Cl)=C2)O1)NC3=CC=C(CN4CCOCC4)C=C3
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	96.04%
CAS	638156-11-3
Solubility Information	DMSO : 20 mg/mL (50.39 mM; Need ultrasonic)
Health Hazard 1	H302∣H319
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₂H₂₁ClN₂O₃
Formula Weight	396.87

Wortmannin, MedChemExpress

MedChemExpress Wortmannin (SL-2052; KY-12420) is a potent, selective and irreversible PI3K inhibitor with an IC50 of 3 nM. Wortmannin also blocks autophagy formation, and potently inhibits Polo-like kinase 1 (PlK1) and Plk3 with IC50s of 5.8 and 48 nM, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	428.43
Color	White
Physical Form	Powder
Chemical Name or Material	Wortmannin
Grade	Research
SMILES	O=C1C([C@@](CC2)([H])[C@@]3(C)C2=O)=C([C@H](OC(C)=O)C3)[C@]4(C)C5=C1OC=C5C(O[C@@H]4COC)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.0%
CAS	19545-26-7
Solubility Information	DMSO : ≥ 50 mg/mL (116.71 mM)
Health Hazard 1	H300∣H310∣H330
Synonym	SL-2052 KY-12420
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₂₄O₈
Formula Weight	428.43

MK2-IN-1 hydrochloride, MedChemExpress

MedChemExpress MK2-IN-1 hydrochloride is a potent and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM) with a non-ATP competitive binding mode.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	509.43
Color	Yellow
Physical Form	Solid
Chemical Name or Material	MK2-IN-1 hydrochloride
Grade	Research
SMILES	O=C(C1=CC=C(C2=CC=C(Cl)C=C2)O1)N(C3=CC=C(N4CCNCC4)C=C3)CC5=NC=CC=C5.[H]Cl
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	97.32%
CAS	1314118-94-9
Solubility Information	DMSO : 100 mg/mL (196.30 mM; Need ultrasonic)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Shelf Life	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molecular Formula	C₂₇H₂₆Cl₂N₄O₂
Formula Weight	509.43

Oglemilast, MedChemExpress

MedChemExpress Oglemilast (GRC 3886) is a potent and orally active phosphodiesterase-4 (PDE4) inhibitor with an IC50 of 0.5 nM for PDE4D3. Oglemilast inhibits pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast has the potential for inflammatory airway diseases.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	516.3
Color	Khaki
Physical Form	Solid
Chemical Name or Material	Oglemilast
Grade	Research
SMILES	O=C(C1=C2C(OC3=CC=C(NS(=O)(C)=O)C=C23)=C(OC(F)F)C=C1)NC4=C(Cl)C=NC=C4Cl
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.2%
CAS	778576-62-8
Solubility Information	DMSO : 4 mg/mL (7.75 mM; Need ultrasonic)
Synonym	GRC 3886
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₁₃Cl₂F₂N₃O₅S
Formula Weight	516.3

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