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Filtered Search Results
Balsalazide, MedChemExpress
MedChemExpress Balsalazide could suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.
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| Molecular Weight (g/mol) | 357.32 |
|---|---|
| Color | Orange |
| Physical Form | Solid |
| Chemical Name or Material | Balsalazide |
| Grade | Research |
| SMILES | O=C(O)C1=CC(/N=N/C2=CC=C(C(NCCC(O)=O)=O)C=C2)=CC=C1O |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 99.2% |
| CAS | 80573-04-2 |
| Solubility Information | DMSO : 100 mg/mL (279.86 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C17H15N3O6 |
| Formula Weight | 357.32 |
SKI II, MedChemExpress
MedChemExpress SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC50 values of 78 μM and 45 μM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation.
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| Molecular Weight (g/mol) | 302.78 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | SKI II |
| Grade | Research |
| SMILES | OC1=CC=C(NC2=NC(C3=CC=C(Cl)C=C3)=CS2)C=C1 |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 99.88% |
| CAS | 312636-16-1 |
| Solubility Information | DMSO : ≥ 100 mg/mL (330.27 mM) |
| Health Hazard 1 | H302 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C15H11ClN2OS |
| Formula Weight | 302.78 |
OTS514, MedChemExpress
MedChemExpress OTS514 is a highly potent TOPK inhibitor with an IC50 of 2.6 nM. OTS514 strongly suppresses the growth of TOPK-positive cancer cells. OTS514 induces cell cycle arrest and apoptosis.
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| Molecular Weight (g/mol) | 364.46 |
|---|---|
| Color | Earth Yellow |
| Physical Form | Solid |
| Chemical Name or Material | OTS514 |
| Grade | Research |
| SMILES | O=C1NC2=C(C(C3=CC=C([C@@H](C)CN)C=C3)=C(O)C=C2C)C4=C1SC=C4 |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.15% |
| CAS | 1338540-63-8 |
| Solubility Information | DMSO : 100 mg/mL (274.38 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C21H20N2O2S |
| Formula Weight | 364.46 |
inS3-54A18, MedChemExpress
MedChemExpress inS3-54A18 is a potent STAT3 inhibitor, with anti-cancer properties.
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| Molecular Weight (g/mol) | 373.83 |
|---|---|
| Color | Orange |
| Physical Form | Solid |
| Chemical Name or Material | inS3-54A18 |
| Grade | Research |
| SMILES | O=C1N(C2=CC=C(O)C=C2)C(C3=CC=CC=C3)=C/C1=C/C4=CC=C(Cl)C=C4 |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 99.83% |
| CAS | 328998-53-4 |
| Solubility Information | DMSO : ≥ 150 mg/mL (401.25 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C23H16ClNO2 |
| Formula Weight | 373.83 |
Acetaminophen metabolite 3-hydroxy-acetaminophen, MedChemExpress
MedChemExpress 3-hydroxy-acetaminophen is a metabolite of Acetaminophen, which is a pain medicine.
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| Molecular Weight (g/mol) | 167.16 |
|---|---|
| Color | Gray |
| Physical Form | Solid |
| Chemical Name or Material | Acetaminophen metabolite 3-hydroxy-acetaminophen |
| Grade | Research |
| SMILES | OC1=C(O)C=C(NC(C)=O)C=C1 |
| For Use With (Application) | Neuroscience-Neuromodulation |
| Percent Purity | 99.03% |
| CAS | 37519-14-5 |
| Solubility Information | DMSO : 250 mg/mL (1495.57 mM; Need ultrasonic) |
| Health Hazard 1 | H302∣H315∣H319∣H335 |
| Synonym | 3-Hydroxyacetaminophen |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C8H9NO3 |
| Formula Weight | 167.16 |
Fenretinide, MedChemExpress
MedChemExpress Fenretinide (4-HPR) is a synthetic retinoid deriverative, binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death.
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| Molecular Weight (g/mol) | 391.55 |
|---|---|
| Color | Yellow |
| Physical Form | Solid |
| Chemical Name or Material | Fenretinide |
| Grade | Research |
| SMILES | CC(/C=C/C=C(/C=C/C1=C(CCCC(C)1C)C)C)=C\C(NC2=CC=C(O)C=C2)=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 99.08% |
| CAS | 65646-68-6 |
| Solubility Information | DMSO : ≥ 130 mg/mL (332.01 mM) |
| Health Hazard 1 | H302+H312+H332∣H315∣H319∣H335∣H360 |
| Synonym | 4-HPR |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C26H33NO2 |
| Formula Weight | 391.55 |
Osalmid, MedChemExpress
MedChemExpress Osalmid is a ribonucleotide reductase small subunit M2 (RRM2) targeting compound; suppresses ribonucleotide reductase activity with an IC50 of 8.23 μM.
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| Molecular Weight (g/mol) | 229.23 |
|---|---|
| Color | Off-White |
| Physical Form | Solid |
| Chemical Name or Material | Osalmid |
| Grade | Research |
| SMILES | O=C(NC1=CC=C(O)C=C1)C2=CC=CC=C2O |
| For Use With (Application) | COVID-19-anti-virus |
| Percent Purity | 99.85% |
| CAS | 526-18-1 |
| Solubility Information | DMSO : ≥ 100 mg/mL (436.24 mM) |
| Health Hazard 1 | H302∣H315∣H319 |
| Synonym | Oxaphenamide 4'-Hydroxysalicylanilide |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C13H11NO3 |
| Formula Weight | 229.23 |
OTS964 hydrochloride, MedChemExpress
MedChemExpress OTS964 hydrochloride is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor with an IC50 of 28 nM. OTS964 hydrochloride is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a Kd of 40 nM.
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| Molecular Weight (g/mol) | 428.97 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | OTS964 hydrochloride |
| Grade | Research |
| SMILES | OC1=CC(C)=C2C(C3=C(SC=C3)C(N2)=O)=C1C4=CC=C([C@@H](C)CN(C)C)C=C4.Cl |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 95.59% |
| CAS | 1338545-07-5 |
| Solubility Information | DMSO : ≥ 83.33 mg/mL (194.26 mM) ∣H2O : 1.43 mg/mL (3.33 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture) |
| Shelf Life | 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture) |
| Molecular Formula | C23H25ClN2O2S |
| Formula Weight | 428.97 |
JANEX-1, MedChemExpress
MedChemExpress JANEX-1 (WHI-P131) is a potent and specific JAK3 inhibitor (estimated Ki=2.3 μM). JANEX-1 (WHI-P131) shows potent JAK3-inhibitory activity (IC50 of 78 μM), does not inhibit JAK1 and JAK2.
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| Molecular Weight (g/mol) | 297.31 |
|---|---|
| Color | Gray |
| Physical Form | Solid |
| Chemical Name or Material | JANEX-1 |
| Grade | Research |
| SMILES | OC1=CC=C(NC2=C3C=C(OC)C(OC)=CC3=NC=N2)C=C1 |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 99.6% |
| CAS | 202475-60-3 |
| Solubility Information | DMSO : ≥ 100 mg/mL (336.35 mM) |
| Health Hazard 1 | H302∣H315∣H319∣H335 |
| Synonym | WHI-P131 Jak3 inhibitor I |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C16H15N3O3 |
| Formula Weight | 297.31 |
Birabresib, MedChemExpress
MedChemExpress Birabresib (OTX-015) is a potent bromodomain (BRD2/3/4) inhibitor with IC50s ranging from 92 to 112 nM.
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| Molecular Weight (g/mol) | 491.99 |
|---|---|
| Color | Light Brown |
| Physical Form | Solid |
| Chemical Name or Material | Birabresib |
| Grade | Research |
| SMILES | O=C(NC1=CC=C(O)C=C1)C[C@H]2C3=NN=C(C)N3C4=C(C(C)=C(C)S4)C(C5=CC=C(Cl)C=C5)=N2 |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.19% |
| CAS | 202590-98-5 |
| Solubility Information | DMSO : ≥ 49 mg/mL (99.60 mM) |
| Health Hazard 1 | H302∣H315∣H319∣H335 |
| Synonym | OTX-015 MK-8628 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C25H22ClN5O2S |
| Formula Weight | 491.99 |
Amodiaquine dihydrochloride dihydrate, MedChemExpress
MedChemExpress Amodiaquine dihydrochloride dihydrate (Amodiaquin dihydrochloride dihydrate), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine dihydrochloride dihydrate is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ∼20 μM. Anti-inflammatory effect.
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