CAS RN 147536-97-8

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Tocris Bioscience™ Bosentan

High affinity dual ETA and ETB receptor antagonist;orally bioavailable

Pricing and Availability
Specifications

Target	Non-selective Endothelin Receptor
CAS	147536-97-8
Product Type	Antagonist
Recommended Storage	Store at 4°C
Molecular Formula	C₂₇H₂₉N₅O₆S
Formula Weight	551.61g/mol

Bosentan, MedChemExpress

MedChemExpress Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	551.61
Color	Off-White
Physical Form	Solid
Chemical Name or Material	Bosentan
Grade	Research
SMILES	O=S(NC1=NC(C2=NC=CC=N2)=NC(OCCO)=C1OC3=CC=CC=C3OC)(C4=CC=C(C(C)(C)C)C=C4)=O
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.58%
CAS	147536-97-8
Solubility Information	DMSO : ≥ 100 mg/mL (181.29 mM)
Health Hazard 1	H302∣H361∣H410
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₇H₂₉N₅O₆S
Formula Weight	551.61

CAS RN 147536-97-8

CAS RN 147536-97-8

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Tocris Bioscience™ Bosentan Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ Bosentan