CAS RN 196868-63-0
CAS RN 196868-63-0
IUPAC Name:
1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
Synonyms:
1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
Molecular Weight (g/mol):
341.8
Molecular Formula:
C18H16ClN3O2
InChi Key:
YBLWOZUPHDKFOT-UHFFFAOYSA-N
SMILES:
COC1=C(NC(=O)NC2=C3C=CC=CC3=NC(C)=C2)C=C(Cl)C=C1
1
–
2
of
2
results
1
Tocris Bioscience™ PQ 401
CAS: 196868-63-0 Molecular Formula: C18H16ClN3O2
2
PQ401, MedChemExpress
MedChemExpress PQ401 is a potent inhibitor of IGF-IR signaling. PQ401 inhibits IGF-I-stimulated IGF-IR autophosphorylation with an IC50 of 12.0 μM in a series of studies in MCF-7 cells. PQ401 is effective at inhibiting IGF-I-stimulated growth of MCF-7 cells (IC50, 6 μM). PQ401 is a potential agent for breast and other IGF-I-sensitive cancers. PQ401 induces caspase-mediated apoptosis.
