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CAS RN 36945-98-9

OHNHNONOO

CAS RN 36945-98-9

IUPAC Name: 3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-1,2,3,4-tetrahydropyrimidin-2-one
Synonyms: icilin
Molecular Weight (g/mol): 311.3
Molecular Formula: C16H13N3O4
InChi Key: RCEFMOGVOYEGJN-UHFFFAOYSA-N
SMILES: OC1=CC=CC=C1N1CC=C(NC1=O)C1=CC=CC(=C1)[N+]([O-])=O
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Tocris Bioscience™ Icilin
GREENER_CHOICE

CAS: 36945-98-9 Molecular Formula: C16H13N3O4

CAS 36945-98-9
Molecular Formula C16H13N3O4
2

Icilin, MedChemExpress

MedChemExpress Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 (TRPM8) ion channel. Icilin activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM). Icilin is a 'super-cooling agent'. Icilin attenuates autoimmune neuroinflammation through modulation of the T-cell response.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 311.29
Color Yellow
Physical Form Solid
Chemical Name or Material Icilin
Grade Research
SMILES O=C1N(C2=CC=CC=C2O)CC=C(C3=CC=CC([N+]([O-])=O)=C3)N1
For Use With (Application) Cancer-Kinase/protease
Percent Purity 95.0%
CAS 36945-98-9
Solubility Information DMSO : ≥ 54 mg/mL (173.47 mM)
Health Hazard 1 H302∣H312∣H332
Synonym AG-3-5
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C16H13N3O4
Formula Weight 311.29