CAS RN 383432-38-0

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CP-724714, MedChemExpress

MedChemExpress CP-724714 is a potent, selective and orally active ErbB2 (HER2) tyrosine kinase inhibitor, with an IC50 of 10 nM. CP-724714 displays a marked selectivity against EGFR kinase (IC50=6400 nM). CP-724714 potently inhibits ErbB2 receptor autophosphorylation in intact cells. Antitumor activities.

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Specifications

Molecular Weight (g/mol)	469.53
Color	Yellow
Physical Form	Solid
Chemical Name or Material	CP-724714
Grade	Research
SMILES	O=C(COC)NC/C=C/C1=CC2=C(N=CN=C2C=C1)NC3=CC=C(C(C)=C3)OC4=CC=C(N=C4)C.[(E)]
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.0%
CAS	383432-38-0
Solubility Information	DMSO : ≥ 50 mg/mL (106.49 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₇H₂₇N₅O₃
Formula Weight	469.53

CAS RN 383432-38-0

CAS RN 383432-38-0

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