CAS RN 65673-63-4
CAS RN 65673-63-4
IUPAC Name:
ethyl (4R)-2-amino-6-bromo-4-[(1S)-1-cyano-2-ethoxy-2-oxoethyl]-4H-chromene-3-carboxylate
Synonyms:
ethyl (4R)-2-amino-6-bromo-4-[(1S)-1-cyano-2-ethoxy-2-oxoethyl]-4H-chromene-3-carboxylate
Molecular Weight (g/mol):
409.24
Molecular Formula:
C17H17BrN2O5
InChi Key:
SXJDCULZDFWMJC-YPMHNXCESA-N
SMILES:
CCOC(=O)[C@H](C#N)[C@@H]1C2=CC(Br)=CC=C2OC(N)=C1C(=O)OCC
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HA14-1, MedChemExpress
MedChemExpress HA14-1 is a Bcl-2/Bcl-XL antagonist. HA14-1 binds the designated pocket on Bcl-2 with the IC50 of ≈9 μM in competing with the Bcl-2 binding of Flu-BakBH3, and inhibits its function.
