CAS RN 835621-07-3

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Regorafenib Hydrochloride, MedChemExpress

MedChemExpress Regorafenib Hydrochloride (BAY 73-4506 hydrochloride) is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

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Specifications

Molecular Weight (g/mol)	519.28
Color	Off-White
Physical Form	Solid
Chemical Name or Material	Regorafenib Hydrochloride
Grade	Research
SMILES	ClC1=C(C(F)(F)F)C=C(NC(NC2=C(F)C=C(OC3=CC=NC(C(NC)=O)=C3)C=C2)=O)C=C1.Cl
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.0%
CAS	835621-07-3
Solubility Information	DMSO : ≥ 5.6 mg/mL (10.78 mM) ∣H2O : < 0.1 mg/mL (insoluble)
Synonym	BAY 73-4506 hydrochloride
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₂₁H₁₆Cl₂F₄N₄O₃
Formula Weight	519.28

CAS RN 835621-07-3

CAS RN 835621-07-3

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