CAS RN 854107-55-4

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Ponesimod, MedChemExpress

MedChemExpress Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation.

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Specifications

Molecular Weight (g/mol)	460.97
Color	Yellow
Physical Form	Solid
Chemical Name or Material	Ponesimod
Grade	Research
SMILES	O=C1N(C2=CC=CC=C2C)/C(S/C1=C\C3=CC=C(OC[C@H](O)CO)C(Cl)=C3)=N/CCC
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.25%
CAS	854107-55-4
Solubility Information	DMSO : ≥ 100 mg/mL (216.93 mM)
Health Hazard 1	H302∣H315∣H319∣H335
Synonym	ACT-128800
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₂₅ClN₂O₄S
Formula Weight	460.97

CAS RN 854107-55-4

CAS RN 854107-55-4

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