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1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%, Thermo Scientific Chemicals
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Quantity:
1 g
5 g
25 g
Description
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3'-amino-3'-deoxyadenosine-5'-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.
Solubility
Soluble in acetonitrile dichloromethane, dimethylformamide, and tetrahydrofuran. Slightly soluble in water.
Notes
Sensitive to moisture. Incompatible with strong acids, strong oxidizing agents and moisture.
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.
Solubility
Soluble in acetonitrile dichloromethane, dimethylformamide, and tetrahydrofuran. Slightly soluble in water.
Notes
Sensitive to moisture. Incompatible with strong acids, strong oxidizing agents and moisture.
Specifications
| Melting Point | ∽113°C |
| Linear Formula | CH3CH2N=C=N(CH2)3N(CH3)2·HCl |
| Quantity | 5 g |
| Beilstein | 5764110 |
| Sensitivity | Moisture sensitive |
| Solubility Information | Soluble in acetonitrile dichloromethane,dimethylformamide,and tetrahydrofuran. Slightly soluble in water. |
| Formula Weight | 191.7 |
| Percent Purity | ≥98% |
| Chemical Name or Material | 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride |
Safety and Handling
Product Identifier
- 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimidehydrochloride
- Danger
- Acute toxicity Category 3
- Acute toxicity Category 4
- LONG-TERM AQUATIC HAZARD Chronic 1
- ACUTE AQUATIC Acute 1
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Skin sensitiser Category 1
- Specific target organ toxicity after repeated exposure Category 2
- H302-Harmful if swallowed.
- H311-Toxic in contact with skin.
- H315-Causes skin irritation.
- H317-May cause an allergic skin reaction.
- H319-Causes serious eye irritation.
- H373-May cause damage to organs.
- H400-Very toxic to aquatic life.
- H410-Very toxic to aquatic life with long lasting effects.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P312-Call a POISON CENTER/doctor/if you feel unwell.
- MIXTURE LIST-Contains : N'-(ethylcarbonimidoyl)-N,N-dimethyl-1,3-Propanediamine monohydrochloride
RUO – Research Use Only
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