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  5. Tocris Bioscience™ 10-Cl-BBQ

Tocris Bioscience™ 10-Cl-BBQ
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Product Code. 18759676
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25 mg
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18759676 5 mg 5mg
18717906 25 mg 25mg
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Product Code. 18759676 Supplier Tocris Bioscience™ Supplier No. 6321/5

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Description

Potent aryl hydrocarbon receptor (AhR) agonist; orally bioavailable

10-Cl-BBQ is a potent aryl hydrocarbon receptor (AhR) agonist, discovered as a screening hit (IC50 = 2.6 nM). Directly binds CD4+ T cells to induce AhR-dependent Tregs. Suppresses IL-17 production and prevents insulitis in NOD mice. In vivo half llife ∽ 2 hours, orally bioavailable.
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Specifications

Chemical Name or Material 10-Chloro-7H-benzimidazo[2,1-a]benz[de]isoquinolin-7-one
CAS 23982-76-5
Quantity 5 mg
Molecular Formula C18H9ClN2O
Formula Weight 304.73
Purity 97%
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