Invitrogen™ ACSL3/ACSL4 Recombinant Rabbit Monoclonal Antibody (HL1941)

Description

ACSL3/ACSL4 Recombinant Monoclonal Antibody for Western Blot

ACSL3 (Acyl-CoA Synthetase Long-Chain Family Member 3) and ACSL4 (Acyl-CoA Synthetase Long-Chain Family Member 4) are genes that encode enzymes belonging to the acyl-CoA synthetase family. These enzymes play crucial roles in lipid metabolism by catalyzing the activation of long-chain fatty acids through the formation of acyl-CoA. This process is essential for various cellular functions, including lipid biosynthesis, fatty acid degradation, and energy production. ACSL3 is primarily expressed in tissues like the liver and adipose tissue, where it is involved in fatty acid metabolism and lipid storage. ACSL4, on the other hand, is known for its significant role in the brain and in the regulation of inflammatory responses, as well as being implicated in the metabolism of polyunsaturated fatty acids. Dysregulation of ACSL3 and ACSL4 has been linked to several diseases, including metabolic disorders, cancer, and neurological diseases, making them important targets for therapeutic research and drug development.