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Invitrogen™ INSIG1 Recombinant Rabbit Monoclonal Antibody (0Q2B5)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA555473

Product Code. 30131874

  • € 436.00 / 100µL

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Description

Description

Immunogen Sequence: ASAKLDFANN VQLSLTLAAL SLGLWWTFDR SRSGLGLGIT IAFLATLITQ FLVYNGVYQY TSPDFLYIRS WLPCIFFSGG VTVGNIGRQL AMGVPEKPHS D.

Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

INSIG1
Recombinant Monoclonal
1.19 mg/mL
PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Q08755, Q8BGI3
INSIG1
Recombinant fusion protein containing a sequence corresponding to amino acids 177-277 of human INSIG1.
100 μL
Primary
Mouse, Rat
Antibody
IgG
ELISA, Immunohistochemistry (Paraffin)
0Q2B5
Unconjugated
INSIG1
1810013C12Rik; CL6; CL-6; fb55a03; fi35b10; growth response protein (CL-6); immediate-early protein CL-6; INSIG1; INSIG-1; INSIG-1 membrane protein; insulin induced gene 1; insulin induced protein 1; insulin-induced gene 1 protein; Insulin-induced growth response protein CL-6; MGC1405; wu:fb55a03; wu:fi35b10; zgc:55439
Rabbit
Protein A
RUO
231070, 64194
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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