missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ 1A-116

Tocris Bioscience™ 1A-116

Product Code. 18054522
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
This item is not returnable. View return policy

Product Code. 18054522

Brand: Tocris Bioscience™ 6701/10

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Rac1 inhibitor; blocks Rac1-P-Rex1 interaction

1A-116 is a Rac1 inhibitor. Reduces intracellular Rac1-GTP levels and blocks Rac1-P-Rex1 interaction in vitro. Exhibits no effect on GTPase activity of closely related Cdc42. Displays antiproliferative, anti-invasive and pro-apoptotic activity in several cancer cell lines. Exhibits antimetastatic activity in vivo. Also restores antiproliferative effects of Tamoxifen (Cat. No. 6342) in resistant breast cancer cell.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-(3,5-Dimethylphenyl)-N-[2-(trifluoromethyl)phenyl]guanidine
CAS 1430208-73-3
Quantity 10 mg
Molecular Formula C16H16F3N3
Formula Weight 307.31
Product Type Inhibitor
Purity 98%
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.