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Thermo Scientific™ 2'-Fluoro-iBu-G Phosphoramidite, standard grade, 28-400 finish bottle

Product Code. 17927192 Shop All Thermo Scientific Products
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Quantity:
0.5 g
Unit Size:
500mg
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Product Code. 17927192

Brand: Thermo Scientific™ 27160712

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This item is not returnable. View return policy

Description

2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis.

2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.

Features:
• Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-fluoroguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula: C44H53FN7O8P
• Base: G
• Base Protection: iBu
• Formula weight: 857.4 g/mol
• CAS number: 144089-97-4
• HPLC purity: >98%
• 31P NMR purity: ≥98%

TRUSTED_SUSTAINABILITY

Specifications

For Use With (Equipment) MerMade Synthesizers
Product Type 2in-Fluoro-iBu-G CEP
Content And Storage Store in freezer (at or below -20°C).
Nucleoside Type Guanosine (G)
Reagent Features 2in-Fluoro modified
Shipping Condition Room Temperature
Purity 98%
Quantity 0.5 g
Reagent Type Phosphoramidite
Grade Standard
Nucleic Acid Type RNA
Form Powder
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For Research Use Only. Not for use in diagnostic procedures.

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