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Tocris Bioscience™ Pregnenolone sulfate sodium salt
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Product Code. 18724049
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Quantity:
50 mg
Unit Size:
50mg
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Product Code. 18724049

Brand: Tocris Bioscience™ 5376/50

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This item is not returnable. View return policy

Description

NMDA potentiator; also GABAA inhibitor and TRPM3 activator

Pregnenolone sulfate sodium salt is a highly potent neurosteroid with multiple actions. Enhances intracellular Ca2+ upon NMDA receptor-mediated synaptic activity (EC50 ∽ 2 pM) and potentiates NMDA responses. Inhibitor at GABAA receptors (IC50 values are 0.4 to >300 μM, depending on specific subunit conformation). Activates CREB phosphorylation, augments LTP and cognitive behavior in rat memory models. Also activates TRPM3 channels.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 50 mg
Product Type Pregnenolone sulfate sodium salt
Molecular Weight (g/mol) 418.52
Inhibitors Pregnenolone sulfate sodium salt

For Research Use Only

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