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6-Aminohexanoic acid, 99%, Thermo Scientific Chemicals

Product Code. 11417746
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Quantity:
100 g
500 g
2500 g

6-aminohexanoic acid, CAS # 60-32-2, is a synthetic lysine derivative with inhibitory activity against fibrinolysis. It shows hematologic activity.

6-Aminohexanoic acid is used as an intermediate in the polymerization of Nylon-6. It is involved in the extraction of aldehydes from the reaction mixture as well as to improve the solubilization of membrane proteins in electrophoresis. It acts as an inhibitor of fibrinolysis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • 6-aminohexanoic acid, an epsilon-amino acid, shows an antifibrinolytic and hematologic activity
  • This compound competitively inhibits the activation of plasminogen; it consequently reduces the conversion of plasminogen to plasmin (fibrinolysin), an enzyme responsible for the degradation of fibrin clots, fibrinogen, and other plasma proteins, including the procoagulant factors V and VIII

Application

  • It has been used as an intermediate in the polymerization of Nylon-6
  • It is used for biomolecular applications to extract aldehydes from the reaction mixture and to increase membrane protein solubilization in electrophoresis experiments
  • It has been described to inhibit plasminogen binding to activated platelets
  • This compound can bind and inactivate carboxypeptidase B
  • This compound can also inhibit the activation of the first component of the complement system
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 60-32-2
Molecular Formula C6H13NO2
Molecular Weight (g/mol) 131.175
MDL Number MFCD00008238
InChI Key SLXKOJJOQWFEFD-UHFFFAOYSA-N
Synonym 6-aminocaproic acid, aminocaproic acid, amicar, epsikapron, capramol, caprocid, epsamon, eaca, acepramin, caprolisin
PubChem CID 564
ChEBI CHEBI:16586
IUPAC Name 6-aminohexanoic acid
SMILES C(CCC(=O)O)CCN

Specifications

Melting Point 210°C to 212°C
Assay Percent Range ≥99%
Linear Formula H2N(CH2)5CO2H
Quantity 100 g
Beilstein 906872
Merck Index 14,432
Solubility Information Soluble in water. Slightly soluble in alcohol. Practically insoluble in ether and chloroform.
Formula Weight 131.18
Percent Purity 99%
Chemical Name or Material 6-Aminocaproic Acid
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Product Identifier
  • 6-Aminohexanoic acid
Signal Word
  • Warning
Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Supplemental information
  • MIXTURE LIST-Contains : 6-Aminohexanoic acid

RUO – Research Use Only

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