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A-196, MedChemExpress

Product Code. 16414256
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Product Code. 16414256

Brand: Medchem Express HY100201

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Description

MedChemExpress A-196 is a potent and selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 25 nM and 144 nM, respectively. A-196 inhibits SUV4-20 biochemically in a substrate-competitive manner. A-196 represents a first-in-class chemical probe of SUV4-20 to investigate the role of histone methyltransferases in genomic integrity.

A-196 is a potent and selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 25 nM and 144 nM, respectively. A-196 inhibits SUV4-20 biochemically in a substrate-competitive manner. A-196 represents a first-in-class chemical probe of SUV4-20 to investigate the role of histone methyltransferases in genomic integrity.

Specifications

Chemical Name or Material A-196
Physical Form Solid
CAS 1982372-88-2
Color Off-White
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C18H16Cl2N4
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : ≥ 31 mg/mL (86.29 mM)
SMILES ClC1=C(Cl)C=C(C(C2=CC=NC=C2)=NN=C3NC4CCCC4)C3=C1
Molecular Weight (g/mol) 359.25
Formula Weight 359.25
Percent Purity 99.61%
Grade Research
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Research purposes only

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