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Invitrogen™ A2M Polyclonal Antibody
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Product Code. 17711794
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Quantity:
100 μL
Unit Size:
100µL
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17711794 100 μL 100µL
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Product Code. 17711794 Supplier Invitrogen™ Supplier No. PA5120391

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Description

Rabbit Polyclonal Antibody

Positive test controls include: SH-SY5Y, Mouse kidney, Mouse ovary, Rat spinal cord. The target is usually found in the following locations: Secreted. Immunogen sequence: ALAGNQDKRK EVLKSLNEEA VKKDNSVHWE RPQKPKAPVG HFYEPQAPSA EVEMTSYVLL AYLTAQPAPT SEDLTSATNI VKWITKQQNA QGGFSSTQDT VVALHALSKY GAATFTRTGK AAQVTIQSSG TFSSKFQVDN NNRLLLQQVS LPELPGEYSM KVTGEGCVYL QTSLKYNILP EKEEFPFALG VQTLPQTCDE PKAHTSFQIS LSVSYTGSRS ASNMAIVDVK MVSGFIPLKP TVKMLERSNH VSRTEVSSNH VLIYLDKVSN QTLSLFFTVL QDVPVRDLKP AIVKVYDYYE TDEFAIAEYN APCSKDLGNA.

Alpha 2-Macroglobulin (a2M), is a approximately 720-kDa homotetrameric glycoprotein composed of four identical approximately 180 kDa subunits. aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregnancy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer's disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.
TRUSTED_SUSTAINABILITY

Specifications

Antigen A2M
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.65 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene A2M
Gene Accession No. P01023, P06238, Q6GQT1
Gene Alias A2M; A2m1; A2maa; A2MAC1; A2MD; A2mp; Alpha 2 M; Alpha-2-M; Alpha-2-M (A2M); alpha-2-macroglobulin; Alpha-2-macroglobulin-P; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; DKFZp779B086; FWP007; LOC100061656; Mam; S863 7; S863-7
Gene Symbols A2M
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2, 232345, 24153
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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