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Invitrogen™ ABCA1 Monoclonal Antibody (5A1-1422.11)
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Product Code. 11594422
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
11594422 100 μL 100µL
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Product Code. 11594422 Supplier Invitrogen™ Supplier No. MA116937

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Description

Rat Monoclonal Antibody

This antibody is not reactive in Western blot or ELISA applications.

Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCA1
Applications Flow Cytometry
Classification Monoclonal
Clone 5A1-1422.11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Abca1
Gene Accession No. P41233
Gene Alias ABC 1; ABC 1 antibody; ABC Transporter 1; Abc1; ABC-1; ABC1 antibody; Abca1; ATP binding cassette subfamily A member 1; ATP-binding cassette 1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ATP-binding cassette transporter A1; ATP-binding cassette, subfamily A (ABC1), member 1; ATP-binding cassette, sub-family A (ABC1), member 1; ATP-binding cassette, sub-family A member 1; CERP; CERP antibody; Cholesterol efflux regulatory protein; HDLDT1; membrane-bound; phospholipid-transporting ATPase ABCA1; phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; TGD
Gene Symbols Abca1
Host Species Rat
Immunogen Mouse ABCA1 expressing HeLa stable transfectants.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11303
Target Species Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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