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ABCB1 Monoclonal Antibody (OTI3C8), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA801003
This item is not returnable.
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Description
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.Specifications
| ABCB1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P08183 | |
| ABCB1 | |
| Human recombit protein fragment corresponding to amino acids 995-1280 of human ABCB1 produced in SF9 cell. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin) | |
| OTI3C8 | |
| Unconjugated | |
| ABCB1 | |
| ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 5243 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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