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Invitrogen™ Human ABL1 [F317L], GST Tag Recombinant Protein

This ABL1 F317L Recombinant Human Protein (27-end) was expressed in insect cells.

€ 524.00 - € 7580.00

Specifications

Accession Number NP_005148.2
For Use With (Application) Kinase Assay
Molecular Weight (g/mol) 146.3 kDa
KinaseFamily ABL Kinase Family
Protein Length aa 27 - end
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15940403
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Invitrogen™
A33475
10 μg
€ 524.00
10µg
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Estimated Shipment: 27-05-2024
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17198805
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Invitrogen™
A33550
100 μg
€ 2435.00
100µg
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Estimated Shipment: 28-05-2024
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17118835
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Invitrogen™
A33719
1 mg
€ 7580.00
1mg
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Estimated Shipment: 22-07-2024
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Description

Description

ABL1 cytoplasmic tyrosine kinase protooncogene encodes a cytoplasmic and nuclear kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of ABL protein is negatively regulated by its SH3 domain and deletion of the SH3 domain turns ABL1 into an oncogene. Translocation and head-to-tail fusion of the BCR and ABL1 genes is present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDK1-mediated phosphorylation, suggesting a cell cycle function for ABL1.
  • Validated for use with the Z’-LYTE™ assay
  • Available in multiple pack sizes for convenient use
Specifications

Specifications

NP_005148.2
146.3 kDa
aa 27 - end
Recombinant
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Recombinant, Active, Mutant
Kinase Assay
ABL Kinase Family
Human
GST Tag
Dry Ice
Liquid
Videos
SDS
Documents

Documents

Product Certifications