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Tocris Bioscience™ AC 265347
GREENER_CHOICE

CaSR biased allosteric modulator

Brand:  Tocris Bioscience™ 6165/10

Encompass

Product Code. 15756369

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Description

Description

AC 265347 is a CaSR biased allosteric modulator (pEC50 = 7.8-8.1). Calcimimetic. Displays ability to bias signalling towards the accumulation of pERK1/2 and IP1. Reduces parathyroid hormone (PTH) levels in rat serum without inducing the release of calcitonin. Exhibits no significant activation of human GABAB or type I PTH receptors. Orally active.
Specifications

Specifications

α-(2,4-Dimethylphenyl)-α-methyl-2-benzothiazolemethanol
1253901-26-6
>99%
10 mg
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