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Invitrogen™ ACSL4 Monoclonal Antibody (GT186)

Description
Keep as concentrated solution. Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%). Positive Control: HeLa. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
Specifications
Specifications
| Antigen | ACSL4 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | GT186 |
| Concentration | 1.28 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with no preservative |
| Gene | Acsl4 |
| Gene Accession No. | O35547, O60488, Q9QUJ7 |
| Gene Alias | 9430020A05Rik; Acs4; ACSL4; acyl-CoA synthetase 4; acyl-CoA synthetase long-chain family member 4; Arachidonate--CoA ligase; AU018108; Facl4; fatty acid Coenzyme A ligase, long chain 4; fatty acid-Coenzyme A ligase long chain 4; fatty acid-Coenzyme A ligase, long chain 4; fatty-acid-Coenzyme A ligase, long-chain 4; L MRX63; LACS 4; Lacs4; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 4; long-chain fatty-acid-Coenzyme A ligase 4; long-chain-fatty-acid--CoA ligase 4; mACS4; MRX63; MRX68 |
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