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Invitrogen™ ACSL6 Polyclonal Antibody
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Product Code. 16698124
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
16698124 100 μL 100µL
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Product Code. 16698124 Supplier Invitrogen™ Supplier No. PA5101652

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ACSL6.

FACL6 is involved in activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. It plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. FACL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derieved from fetal liver, haemopoietic stem cells from cord blood, bone marrow, and brain. Expression is low at earlier stages of erythroid development but is very high in reticulocytes. This protein is involved in myelodysplastic syndrome (MDS) with basophilia, acute myelogenous leukemia (AML) with eosinophilia, and acute eosinophilic leukemia (AEL). It is characterized by a chromosomal translocation t(5;12)(q31;p13) that involves ETV6 and ACSL6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACSL6
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Acsl6
Gene Accession No. P33124, Q91WC3, Q9UKU0
Gene Alias A330035H04Rik; ACS2; ACSL6; acyl-CoA synthetase long-chain family member 6; Arachidonate--CoA ligase; AW050338; FACL6; fatty acid Coenzyme A ligase, long chain 6; fatty-acid-Coenzyme A ligase, long-chain 6; KIAA0837; L LACS5; LACS; LACS 6; LACS2; LACS5; Lacsl; long fatty acyl-CoA synthetase 2; long-chain acyl-CoA synthetase 6; Long-chain-fatty-acid--CoA ligase 6; long-chain-fatty-acid--CoA ligase, brain isozyme; mKIAA0837
Gene Symbols Acsl6
Host Species Rabbit
Immunogen A synthesized peptide derived from human ACSL6(Accession Q9UKU0), corresponding to amino acid residues N498-G548.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117243, 216739, 23305
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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