Learn More
Invitrogen™ ACTA1 Recombinant Rabbit Monoclonal Antibody (8T8D0)

Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA542777
Description
Positive test controls include: HeLa, A-431, RD, C6, Mouse lung, Mouse brain, Mouse heart, Rat lung, Rat heart. The target is usually found in the following locations: Cytoplasm, cytoskeleton. Immunogen sequence: MCDEDETTAL VCDNGSGLVK AGFAGDDAPR AVFPSIVGRP RHQGVMVGMG QKDSYVGDEA QSKRGILTLK YPIEHGIITN WDDMEKIWHH TFYNELRVAP.
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Specifications
| ACTA1 | |
| Recombinant Monoclonal | |
| 0.8 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P68133, P68134, P68136 | |
| ACTA1 | |
| A synthetic peptide corresponding to a sequence within amino acids 1-100 of human alpha Actin-1 (ACTA1). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 8T8D0 | |
| Unconjugated | |
| ACTA1 | |
| AA959943; ACTA; Acta1; Acta-2; actin alpha 1; actin alpha 1, skeletal muscle; actin, alpha 1, skeletal muscle; actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; Acts; Actsk-1; alpha actin 1; alpha-actin-1; ASMA; beta actin; CFTD; CFTD1; CFTDM; cytoplasmic beta-actin; LOW QUALITY PROTEIN: actin, alpha skeletal muscle; MPFD; NEM1; NEM2; NEM3; nemaline myopathy type 3; SHPM; skeletal alpha actin; unnamed protein product | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 11459, 29437, 58 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
Your input is important to us. Please complete this form to provide feedback related to the content on this product.