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ADAMTS4 Monoclonal Antibody (OTI2G8), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA805430
This item is not returnable.
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Description
This gene encodes a member of the ADAMTS protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.Specifications
| ADAMTS4 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| O75173 | |
| ADAMTS4 | |
| Human recombit protein fragment corresponding to amino acids 296-577 of human ADAMTS4 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI2G8 | |
| Unconjugated | |
| ADAMTS4 | |
| ADAMTS-2, ADAMTS-4, ADMP-1 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 9507 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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