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Novus Biologicals™ Recombinant Human Osteoprotegerin/TNFRSF11B Fc fusion Protein
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Description
Osteoprotegerin/TNFRSF11B protein is fully biologically active when compared to standard. The ED50 as determined by neutralizing the stimulation of U937 cells is less than 10 ng/mL, corresponding to a specific activity of > 1.0 x 10^5 IU/mg in the presence of 10 ng/mL soluble rHuRANKL (sRANKL).
Specifications
Specifications
| For Use With (Application) | Bioactivity |
| Formulation | Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 6.0, 150 mM NaCl, 0.02 % Tween-80. |
| Gene ID (Entrez) | 4982 |
| Molecular Weight (g/mol) | MolecularWeight-theroretical: 109.6 kDa |
| Quantity | 500 μg |
| Storage Requirements | Store at -20°C to -70°C as supplied. After reconstitution, store at 2 to 8 C for 1 month and (at -20°C to -70°C for long term storage. Avoid repeated freeze/thaw cycles.) |
| Endotoxin Concentration | Less than 1 EU/μg of Osteoprotegerin/TNFRSF11B as determined by LAL method. |
| Gene Alias | OCIFMGC29565, OPG, OPGtumor necrosis factor receptor superfamily member 11 B, Osteoclastogenesis inhibitory factor, Osteoprotegerin, TR1, tumor necrosis factor receptor superfamily, member 11 b |
| Gene Symbol | TNFRSF11B |
| Reconstitution | Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL Apportion stock solutions into working aliquots and store (at <-20°C.) |
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