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Invitrogen™ AHA1 Monoclonal Antibody (25F2.D10), APC

Rat Monoclonal Antibody
Brand: Invitrogen™ MA545237
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Description
1 μg/mL of MA5-45237 was sufficient for detection of Aha1 in 10 μg of rat tissue lysate by colorimetric immunoblot analysis using Goat anti-rat IgG:HRP as the secondary antibody. Detects approximately 38kDa. Can run up to 45kDa on SDS Page.
Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155). Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155). [UniProt].
Specifications
| AHA1 | |
| Monoclonal | |
| 1.59 mg/mL | |
| 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.6 | |
| O95433, Q8BK64 | |
| Ahsa1 | |
| Mouse Aha1. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG2a κ |
| ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| 25F2.D10 | |
| APC | |
| Ahsa1 | |
| Activator of 90 kDa heat shock protein ATPase homolog 1; activator of Hsp90 ATPase activity 1; Activator of Hsp90 ATPase protein 1; Aha 1; AHA1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast); AHA1, activator of heat shock protein ATPase 1; AHA1, activator of heat shock protein ATPase homolog 1; Aha1p; AHSA 1; Ahsa1; BC023857; C14orf3; hAha1; Hsp90 co-chaperone AHA1; HSPC322; p38; SHSA1; YD8142.16; YD8142B.06; YDR214W | |
| Rat | |
| Protein G | |
| RUO | |
| 10598, 217737, 681996 | |
| 4°C | |
| Liquid |
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