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AIRE Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 22517-1-AP-20UL
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Description
The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).Specifications
| AIRE | |
| Polyclonal | |
| Unconjugated | |
| AIRE | |
| AIRE, AIRE1, APECED, APECED protein, APS1, APSI, autoimmune regulator, PGA1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 11634, 326 | |
| -20°C | |
| Liquid |
| Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| 0.27 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| O43918, Q9Z0E3 | |
| AIRE | |
| AIRE Fusion Protein Ag18249 | |
| 20 μL | |
| Primary | |
| Mouse, Human | |
| Antibody | |
| IgG |
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