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Invitrogen™ AKAP10 Polyclonal Antibody

Description
This antibody detects endogenous protein at a molecular weight of 74 kDa. Purity is >95% by SDS-PAGE.
The A-kinase anchor proteins are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.
Specifications
Specifications
| Antigen | AKAP10 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | AKAP10 |
| Gene Accession No. | O43572 |
| Gene Alias | 1500031L16Rik; A kinase (PRKA) anchor protein 10; A kinase anchor protein 10; A kinase anchor protein 10, mitochondrial; Akap10; AKAP-10; A-kinase anchor protein 10, mitochondrial; A-kinase anchoring protein 10; B130049N18Rik; D-akap2; D-AKAP-2; Dual specific A kinase anchoring protein 2; dual specificity A kinase-anchoring protein 2; MGC9414; mitochondrial A kinase PPKA anchor protein 10; PRKA10; protein kinase A anchoring protein 10; protein kinase A-anchoring protein 10 |
| Gene Symbols | AKAP10 |
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