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AKAP10 Polyclonal Antibody, Invitrogen™

Product Code. 15535451
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Quantity:
100 μg
Unit Size:
100µg
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15535451 100 μg 100µg
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Product Code. 15535451 Supplier Invitrogen Supplier No. PA538529

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Description

Rabbit Polyclonal Antibody

AKAP 10 (A kinase anchor protein 10), also known as PRKA10 or D-AKAP2 (dual-specific A kinase-anchoring protein 2), is a 662 amino acid mitochondrial membrane protein that belongs to the AKAP family. AKAP 10 is a dual specificity protein that binds to both type I and type II regulatory subunits of PKA and anchors them to the plasma membrane or the mitochondria. When anchored to the mitochondria, PKA can phosphorylate and, thus, inactivate the proapoptotic protein Bad. This suggests that AKAP 10 indirectly regulates Bad-induced apoptosis by mediating the mitochondrial attachment of PKA. Additionally, AKAP 10 may facilitate G-protein coupled signal transduction and could act as an adaptor in the assembly of multiprotein complexes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AKAP10
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene AKAP10
Gene Accession No. O43572, O88845
Gene Alias A-kinase anchor protein 10, mitochondrial, AKAP-10, Dual specificity A kinase-anchoring protein 2, D-AKAP-2, Protein kinase A-anchoring protein 10, PRKA10, AKAP10
Gene Symbols AKAP10
Host Species Rabbit
Immunogen A synthetic peptide derived from the internal region of human AKAP10
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11216, 360540, 56697
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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