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Invitrogen™ AKR1C1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA521672

Product Code. 13259058

  • € 566.00 / 100µg

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Description

Description

Recommended positive controls: A431, HeLa, HepG2, A549, mouse liver. Predicted reactivity: Pig (83%), Rhesus Monkey (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

AKR1C1
Polyclonal
Unconjugated
AKR1C1
17-beta-HSD 5; 17HSD type 5; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); 20-ALPHA-HSD; 20-alpha-hydroxysteroid dehydrogenase; 2-ALPHA-HSD; 3alpha-HSD; Akr1c1; Akr1c6; aldo-keto reductase C; aldo-keto reductase family 1 member C1; aldo-keto reductase family 1, member C1; aldo-keto reductase family 1, member C1 (aldehyde reductase); aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); aldo-keto reductase family 1, member C6; C9; chlordecone reductase homolog HAKRC; DD1; DD1/DD2; DDH; DDH1; dihydrodiol dehydrogenase 1; dihydrodiol dehydrogenase 1/2; dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase; dihydrodiol dehydrogenase isoform DD1; estradiol 17 beta-dehydrogenase 5; estradiol 17-beta-dehydrogenase (A-specific); H-37; HAKRC; HBAB; hepatic dihydrodiol dehydrogenase; high-affinity hepatic bile acid-binding protein; Hsd17b5; hydroxysteroid 17-beta dehydrogenase 5; indanol dehydrogenase; MBAB; RP11-69D4.1; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; type 5 17beta-hydroxysteroid dehydrogenase; type II 3-alpha-hydroxysteroid dehydrogenase
Rabbit
Antigen affinity chromatography
RUO
1645, 83702
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.6 mg/mL
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
P70694, Q04828
AKR1C1, Akr1c6
Recombinant protein encompassing a sequence within the center region of human AKR1C1. The exact sequence is proprietary.
100 μL
Primary
Human, Mouse
Antibody
IgG
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