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AKT1/AKT3 (phospho Y437) Rabbit anti-Human, Mouse, Rat, Polyclonal , Abnova™

Product Code. 16274350
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Quantity:
100 μL
Unit Size:
100µL
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16274350 100 μL 100µL
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Product Code. 16274350 Supplier Abnova Supplier No. PAB29638.100uL

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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human AKT1/AKT3.

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq]

Specifications

Antigen AKT1/AKT3 (phospho Y437)
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human AKT1/AKT3.
Dilution Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:3000) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Alias AKT/MGC99656/PKB/PKB-ALPHA/PRKBA/RAC/RAC-ALPHA
Gene Symbols AKT1
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y437/Y434 of human AKT1/AKT3.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 207/10000
Test Specificity AKT1/AKT3 (phospho Y437/Y434) polyclonal antibody detects endogenous levels of human AKT1/AKT3 only when phosphorylated at tyrosine 437 and tyrosine 434.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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