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Invitrogen™ ALDH1A2 Polyclonal Antibody
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Product Code. 16549541
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Quantity:
100 μL
Unit Size:
100µL
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16549541 100 μL 100µL
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Product Code. 16549541 Supplier Invitrogen™ Supplier No. PA596705

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MTSSKIEMPG EVKADPAALM ASLHLLPSPT PNLEIKYTKI FINNEWQNSE SGRVFPVYNP ATGEQVCEVQ EADKADIDKA VQAARLAFSL GSVWRRMDAS ERGRLLDKLA DLVERDRAVL ATMESLNGGK PFLQAFYVDL QGVIKTFRYY AGWADKIHGM TIPVDGDYFT FTRHEPIGVC; Positive Samples: SW620, 293T, Mouse liver, Mouse kidney, Mouse testis, Mouse lung, Rat liver; Cellular Location: Cytoplasm.

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALDH1A2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.59 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ALDH1A2
Gene Accession No. O94788, Q62148, Q63639
Gene Alias AL1A2; alcohol dehydrogenase family 1, subfamily A2; alcohol dehydrogenase family 1, subfamily A7; aldehyde dehydrogenase 1 family member A2; aldehyde dehydrogenase 1 family, member A2; aldehyde dehydrogenase 1A2; aldehyde dehydrogenase family 1 member A2; aldehyde dehydrogenase family 1, subfamily A2; Aldh1a2; Aldh1a7; AV116159; fb50h01; neckless; nls; nof; no-fin; RALDH 2; RALDH(II); Raldh1; RALDH2; Raldh-2; RALDH2-T; retinal dehydrogenase 2; retinal dehydrogenase, type II; retinaldehyde dehydrogenase 2; retinaldehyde dehydrogenase type 2; retinaldehyde-specific dehydrogenase type 2
Gene Symbols ALDH1A2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ALDH1A2 (NP_7337971).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116676, 19378, 8854
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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