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Invitrogen™ ALDH4A1 Monoclonal Antibody (7E2)

Description
Positive Control: SK-Br-3, HepG2, human liver tissue, human colon cancer tissue, human prostate tissue, human kidney tissue.
ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline.
Specifications
Specifications
| Antigen | ALDH4A1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 7E2 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol, 0.2% BSA and 0.05% sodium azide; pH 7.4 |
| Gene | Aldh4a1 |
| Gene Accession No. | P30038 |
| Gene Alias | A930035F14Rik; Ahd1; Ahd-1; aldehyde dehydrogenase 4 family member A1; aldehyde dehydrogenase 4 family, member A1; aldehyde dehydrogenase 4A1; aldehyde dehydrogenase family 4 member A1; ALDH4; aldh4a1; Aldh5a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; E330022C09; L-glutamate gamma-semialdehyde dehydrogenase; mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase; P5C dehydrogenase; P5cd; P5CDh; P5cdhl; P5cdhs; RP11-128M10.1; similar to aldehyde dehydrogenase 4 family, member A1; Ssdh1; zgc:63592 |
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