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Invitrogen™ ALDH5A1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA520609
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Description
A suggested positive control is mouse liver tissue lysate. PA5-20609 can be used with blocking peptide PEP-0729.
Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.
Specifications
| ALDH5A1 | |
| Polyclonal | |
| Unconjugated | |
| ALDH5A1 | |
| 6330403E24Rik; Ahd1; Ahd-1; aldehyde dehydrogenase 1, mitochondrial; aldehyde dehydrogenase 5 family member A1; aldehyde dehydrogenase 5 family, member A1; aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase); aldehyde dehydrogenase family 5 member A1; aldehyde dehydrogenase family 5, subfamily A1; ALDH5A1; aldhehyde dehydrogenase family 5, subfamily A1; D630032B01Rik; mitochondrial succinate semialdehyde dehydrogenase; NAD(+)-dependent succinic semialdehyde dehydrogenase; OTTMUSG00000000613; SSADH; SSDH; Ssdh1; Succinate-semialdehyde dehydrogenase, mitochondrial; succinic semialdehyde dehydrogenase | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 214579, 291133, 7915 | |
| Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| P51649, P51650, Q8BWF0 | |
| ALDH5A1 | |
| a 22 amino acid peptide near the carboxy terminus of the human Aldh5A1. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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