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Invitrogen™ Aldolase A/B/C Recombinant Rabbit Monoclonal Antibody (PSH01-81)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA556379
This item is not returnable.
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Description
Positive Control: U-87 MG cell lysate, RAW264.7 cell lysate, C6 cell lysate, human brain tissue lysate, mouse brain tissue lysate, mouse pancreas tissue lysate, rat brain tissue lysate, rat pancreas tissue lysate, U-87 MG, mouse brain tissue, rat brain tissue. Tissue Specificity: Group enriched (brain, retina). Subcellular Location: cytoskeleton, cytosol, extracellular exosome, extracellular region. Sequence Similarities: 100% Mouse/Rat. Predicted band size: 110 kDa.
Aldolases are important glycolytic cytosolic enzymes which catalyse the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate. There are three aldolase isozymes coded by three distinct genes in mammals, namely aldolases A, B, and C. Aldolase A is heavily expressed in muscle enzyme and aldolase B is heavily expressed in liver and is regarded as a liver specific enzyme. In the adult, aldolase C is the brain-specific isozyme expressed in astrocytes and a few classes of neurons, notably Purkinje cells. Appropriate antibodies to aldolase C are therefore useful to identify astrocytes in cell culture and sectioned material, and the enzyme may be over expressed in some forms of cancer.
Specifications
| Aldolase A/B/C | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 | |
| P00884, P04075, P05062, P05063, P05064, P05065, P09117, P09972, Q91Y97 | |
| ALDOA, ALDOB, ALDOC | |
| Synthetic peptide within human aldolase c aa 50-100. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| PSH01-81 | |
| Unconjugated | |
| ALDOC | |
| ALDA; ALDB; ALDC | |
| Rabbit | |
| Protein A | |
| RUO | |
| 11674, 11676, 226, 229, 230, 230163, 24189, 24190, 24191 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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