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Invitrogen™ Alpha Sarcoglycan Recombinant Rabbit Monoclonal Antibody (3W3Q10)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA537982
This item is not returnable.
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Description
Positive Samples: Rat heart, Rat skeletal muscle Immunogen sequence: VDALVTLLVP LLVALLLTLL LAYVMCCRRE GRLKRDLATS DIQMVHHCTI HGNTEELRQM AASREVPRPL STLPMFNVHT GERLPPRVDS AQVPLILDQH.
The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers. Four sarcoglycan subunit proteins, designated alpha-, beta-, gamma- and delta-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, beta- and delta-sarcoglycans are associated with epsilon-sarcoglycan, a glycoprotein homologous to alpha-sarcoglycan. Additionally, a complete deficiency in delta-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
Specifications
| Alpha Sarcoglycan | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P82350 | |
| SGCA | |
| A synthetic peptide corresponding to a sequence within amino acids 288-387 of human alpha Sarcoglycan (SGCA) (SGCA) (Q16586). | |
| 100 μL | |
| Primary | |
| Mouse, Rat | |
| Antibody | |
| IgG |
| ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 3W3Q10 | |
| Unconjugated | |
| SGCA | |
| 50 kDa dystrophin-associated glycoprotein; 50DAG; 50kD DAG; adhalin; ADL; Alpha-sarcoglycan; alpha-SG; Asg; DAG2; DMDA2; Dystroglycan 2; Dystroglycan2; dystroglycan-2; LGMD2D; limb girdle muscular dystrophy 2D; sarcoglycan alpha; sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein); sarcoglycan, alpha (dystrophin-associated glycoprotein); SCARMD1; SG alpha; SG-alpha; Sgca | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 20391, 303468 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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