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Invitrogen™ TUBA1A Polyclonal Antibody

Description
Recommended positive controls: 293T, A431, HeLa, HepG2, Jurkat, Raji, HeLa cytosol fraction, Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat-2, Drosophila. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.
Specifications
Specifications
| Antigen | TUBA1A |
| Applications | Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1.92 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 20% glycerol and 0.025% ProClin 300; pH 7 |
| Gene | TUBA1A |
| Gene Accession No. | P02552, P68369, P68370, Q71U36 |
| Gene Alias | alpha 1a antibody; alpha 3 antibody; alpha-tubulin; alpha-tubulin 1; Alpha-tubulin 3; alpha-tubulin 3 antibody; Alpha-tubulin isotype M-alpha-1; B-ALPHA-1; B-ALPHA-1 antibody; brain-specific antibody; Detyrosinated tubulin alpha-1A chain; FLJ25113 antibody; FLJ30169; H2 ALPHA; H2ALPHA; H2-ALPHA; hum-a-tub1; hum-a-tub1 antibody; hum-a-tub2; hum-a-tub2 antibody; LIS3; LIS3 antibody; LOC106557476; M40; MGC117247; MGC16435; OK/SW cl.56; OK/SWcl.56; OK/SW-cl.56; Talpha1 alpha-tubulin; TUBA1; Tuba-1; Tuba1a; TUBA1A antibody; TUBA3; TUBA3 antibody; TUBA6; TUBB1; TUBB5; tubulin alpha 1a; tubulin alpha-1 chain; Tubulin alpha-1A chain; tubulin alpha-1A chain antibody; tubulin alpha-3 chain; tubulin alpha-3 chain antibody; Tubulin B-alpha-1; tubulin B-alpha-1 antibody; tubulin, alpha 1; tubulin, alpha 1 (testis specific); tubulin, alpha 1A; tubulin, alpha 6; tubulin, alpha, brain-specific; unnamed protein product |
| Gene Symbols | TUBA1A |
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Safety and Handling
Product Identifier
- TUBA1A Polyclonal Antibody
- Warning
- Skin sensitiser Category 1
- H317-May cause an allergic skin reaction.
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P272-Contaminated work clothing should not be allowed out of the workplace.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P333+P313-If skin irritation or rash occurs: Get medical advice/attention.
- P362+P364-Take off contaminated clothing and wash it before reuse.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
- MIXTURE LIST-Contain: Glycerin
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