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Invitrogen™ ALS2CR2 Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA518135
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Beschreibung
This antibody is predicted to react with bovine and canine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene.
Spezifikation
| ALS2CR2 | |
| Polyclonal | |
| Unconjugated | |
| STRADB | |
| AA792893; Als2cr2; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog; B830008M19; CALS-21; D1Ucla2; ILP-interacting protein; ILP-interacting protein homolog; ILP-interacting protein ILPIPA; ILPIP; ILPIPA; MGC102916; Papk; polyploidy associated protein kinase; polyploidy associated protein kinase PAPK-A; polyploidy-associated protein kinase; PRO1038; pseudokinase ALS2CR2; RGD1559449; STE20 related adaptor beta; STE20-related kinase adapter protein beta; STE20-related kinase adaptor beta; STRAD beta; Stradb; Syradb | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 55437 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| Q9C0K7 | |
| STRADB | |
| Synthetic peptide sequence (CDFPDEKDSYWEF) corresponding to the C-terminus amino acids of STRADB (aa 406-418). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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