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Invitrogen™ AMIGO1 Monoclonal Antibody (L86/33), PE
Description
1 μg/mL of MA5-45622 was sufficient for detection of AMIGO-1 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 60-80kDa depending on maturity/glycosylation. This antibody was formerly sold as clone S86-36.
Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. [UniProt].
Specifications
Specifications
| Antigen | AMIGO1 |
| Applications | Immunohistochemistry, Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | L86/33 |
| Concentration | 1 mg/mL |
| Conjugate | PE |
| Formulation | 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4 |
| Gene | Amigo1 |
| Gene Accession No. | Q80ZD7, Q80ZD8, Q86WK6 |
| Gene Alias | adhesion molecule with Ig like domain 1; adhesion molecule with Ig-like domain 1; ali2; alivin 2; alivin-2; AMIGO; AMIGO 1; AMIGO1; AMIGO-1; amigo1 {ECO:0000250; amphoretin-induced gene and ORF; amphoterin induced gene and ORF (Amigo); amphoterin-induced gene and ORF; amphoterin-induced protein 1; KIAA1163; MGC25558; OTTHUMP00000013379; RP23 89M15.6; transmembrane protein AMIGO; UniProtKB:Q80ZD8} |
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