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Invitrogen™ AMPK gamma-1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA513795
This item is not returnable.
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Description
This antibody is predicted to react with bovine and porcine based on sequence homology.
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Specifications
| AMPK gamma-1 | |
| Polyclonal | |
| Unconjugated | |
| PRKAG1 | |
| 5'-AMP-activated protein kinase subunit gamma-1; 5'-AMP-activated protein kinase, gamma-1 subunit; AA571379; AMP-activated protein kinase, noncatalytic gamma-1 subunit; ampk gamma; AMPK gamma1; AMPK gamma-1 chain; AMPK subunit gamma-1; AMPKG; BB036179; Prkaac; PRKAG1; Prkga1; Protein kinase AMP-activated gamma; protein kinase AMP-activated non-catalytic subunit gamma 1; protein kinase, AMP-activated, gamma 1 non-catalytic subunit | |
| Rabbit | |
| Ammonium sulfate precipitation, Size-exclusion - Dialysis | |
| RUO | |
| 19082, 5571 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 2 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.4 | |
| O54950, P54619 | |
| PRKAG1 | |
| KLH conjugated synthetic peptide between 265-295 amino acids from the central region of human AMPK gamma (PRKAG1). | |
| 400 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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