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  6. 16161981

activating transcription factor 3, Mouse, Clone: 8G5, Abnova™

Mouse monoclonal antibody raised against a full-length recombinant ATF3.

Brand:  Abnova H00000467-M04.100ug

Product Code. 16161981

  • € 349.00 / 100µg

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Description

Description

Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. [provided by RefSeq

Sequence: MMLQHPGQVSASEVSASAIVPCLSPPGSLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKTECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFIQQIKEGTLQS
Specifications

Specifications

activating transcription factor 3
Monoclonal
Unconjugated
PBS with no preservative; pH 7.4
BC006322
Mouse
Affinity Purified
RUO
Yes
467
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG3 κ
ELISA, Western Blot
8G5
Mouse monoclonal antibody raised against a full length recombinant ATF3.
ATF3
ATF3
ATF3 (AAH06322, 1 a.a. ∼ 181 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
100 μg
Transcription Regulation
Primary
Human
Antibody
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