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Bcl-X Mouse, Unlabeled, Clone: 44, BD
Mouse Monoclonal Antibody
€ 253.48 - € 456.78
Specifications
| Antigen | Bcl-X |
|---|---|
| Clone | 44 |
| Concentration | 250μg/mL |
| Applications | Western Blot |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15865619
|
BD Biosciences
610746 |
50 μg |
 € 255.00 € 253.48 / 1 set Save € 1.52 0.60% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
15875619
|
BD Biosciences
610747 |
150 μg |
€ 458.00 € 456.78 / 1 set Save € 1.22 0.27% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Bcl-x is related to the Bcl-2 protein and can function independently of Bcl-2 in regulating apoptosis (programmed cell death). The bcl-x transcript is expressed in a number of tissues, with the highest levels in the lymphoid and central nervous systems. Two distinct cDNA species, bcl-xL and bcl-xS, have been observed and appear to arise from alternate 5' splice sites located within the first coding exon of the bcl-x gene. Bcl-xL is composed of 233 amino acids and is similar in size and structure to Bcl-2. The Bcl-xS polypeptide shows a deletion of 63 amino acids which consist of the region of Bcl-xL with the highest degree of amino acid identity to Bcl-2. Like Bcl-2, Bcl-xL inhibits cell death upon growth factor withdrawal when transfected into an IL-3-dependent cell line. However, Bcl-xS inhibits Bcl-2 mediated cell survival.Specifications
| Bcl-X | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified |
| 44 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Human, Mouse, Rat | |
| Human Bcl-Xl aa. 18-233 | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
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