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BRAF, Mouse, Clone: 4F4, Abnova™
Mouse monoclonal antibody raised against a partial recombinant BRAF.
Brand: Abnova H00000673-M09.100ug
This item is not returnable.
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Description
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, nonsmall cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq
Sequence: FQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPSpecifications
| BRAF | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_004333 | |
| BRAF | |
| BRAF (NP_004324, 138 a.a. ∼ 231 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a κ |
| ELISA, Western Blot | |
| 4F4 | |
| Mouse monoclonal antibody raised against a partial recombinant BRAF. | |
| BRAF | |
| B-RAF1/BRAF1/FLJ95109/MGC126806/MGC138284/RAFB1 | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| 673 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| Liquid |
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