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Calnexin Mouse, Unlabeled, Clone: 37, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 610524
This item is not returnable.
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Description
Calnexin is a 90kDa integral membrane protein located primarily in the ER. It contains a long N-terminal calcium-binding domain that extends into the lumen of the ER and a short, acidic cytosolic domain. Calnexin associates with several cell surface proteins as they pass through the ER. Since it also forms complexes with other resident ER proteins involved in the Ca2+-dependent retention of proteins, calnexin may act as a chaperone. The amino acid sequence of calnexin is highly conserved among species and is similar in sequence to calreticulin, another Ca2+-binding protein found in the ER. Neither calnexin nor calreticulin contain the calcium-binding motif, known as the “E-F hand” found in the calmodulin family of proteins.
Host Species: Mouse
Clone: 37
Isotype: IgG1
Species Reactivity [for Features Main]: Human
Immunogen: Human Calnein aa. 116-301
Immunofluorescence, Immunoprecipitation
Specifications
| Calnexin | |
| Monoclonal | |
| 250μg/mL | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| 150 μg | |
| Cell Biology | |
| Canine, Human, Mouse, Rat | |
| IgG1 |
| Western Blot | |
| 37 | |
| Unconjugated | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at -20°C. |
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