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CD110 Mouse anti-Human, APC, Clone: 1.6.1, BD
Description
The 1.6.1 monoclonal antibody specifically binds to the human Thrombopoietin Receptor (TPO-R) that is also known as the Myeloproliferative leukemia protein (c-Mpl) or CD110. CD110 is a type I transmembrane glycoprotein and a member of the hematopoietin receptor family. It is expressed on hematopoietic stem cells, a subfraction of hematopoietic precursor cells, cells of the megakaryocytic lineage and platelets. CD110 serves as a receptor for thrombopoietin. Upon binding of thrombopoietin to CD110, megakaryocyte proliferation and differentiation is induced, platelets are produced and stem cells are protected from apoptosis.
Specifications
Specifications
| Antigen | CD110 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 1.6.1 |
| Concentration | 0.2mg/mL |
| Conjugate | APC |
| Description | C-MPL; MPL; MPLV; TPOR; Thrombopoietin receptor |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
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