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CD11b Mouse anti-Rat, APC, Clone: WT.5, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 562102

Product Code. 15811649

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    € 240.00
    € 239.68 / Each
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Description

Description

The WT.5 monoclonal antibody specifically binds to CD11b, the α subunit of Mac-1 found on neutrophils and myeloid cells, but not on lymphocytes. Mac-1 expression is rapidly upregulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface. Mac-1 mediates adhesion to ICAM-1 (CD54) and C3bi. Neutrophil binding to ICAM-1 is blocked by mAb WT.5.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD11b
Monoclonal
0.2mg/mL
Itgam; Integrin αM chain; Mac-1 α chain; Integrin beta 2 alpha subunit
Mouse
Affinity Purified
RUO
Rat
IgA κ
Flow Cytometry
WT.5
APC
Aqueous buffered solution containing ≤0.09% sodium azide.
Rt neutrophils
50 μg
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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