Learn More
CD132 Rat anti-Human, Alexa Fluor 647, Clone: TUGh4, BD
Rat Monoclonal Antibody
Brand: BD Biosciences 563682
Description
The TUGh4 monoclonal antibody specifically binds to CD132. CD132 is a 65-70 kDa type 1 transmembrane glycoprotein that is encoded by the IL2RG (interleukin 2 receptor, gamma) gene. CD132 is also known as the common γsubunit (γc) and is shared by the IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21 receptor complexes. CD132 is broadly expressed by most peripheral T and B lymphocytes, NK cells, monocytes, and g ranulocytes. The cytoplasmic domain of the γc chain plays an important role in cytokine-mediated signal transduction. Mutation of the IL2RG gene results in X-linked severe combined immunodeficiency (XSCID). The TUGh4 antibody recognizes a different epitope from that recognized by the CD132-specific clone, AG184.
Specifications
| CD132 | |
| Monoclonal | |
| Alexa Fluor 647 | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG2b κ |
| Flow Cytometry | |
| TUGh4 | |
| IL-2RG; IL-2Rγ; γc; Common γ chain; Common gamma chain; gamma c; SCIDX1 | |
| Human γc Transfected Cell Line | |
| 50 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Your input is important to us. Please complete this form to provide feedback related to the content on this product.